Woman of the Week: Glympse Bio’s Dr. Tram Tran

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Coming out of stealth mode last year, Glympse Bio is now primed to accelerate its platform that uses proteins in the blood to diagnose some of the world’s deadliest diseases.

Dr. Tram Tran took on the company’s first chief medical role just about a year ago, drawn in by Glympse’s revolutionary technology. Rather than injecting biosensors into a patient to get a diagnostic reading, Glympses technology can accomplish that reading with just a blood draw combined with biosensors. The first target is the liver disease nonalcoholic steatohepatitis (NASH), and then the company will focus on oncology — but according to Tran there is no real limit to the disease targets that can be identified.

We figured out how to take blood from the patient and use biosensors to measure protease activity against disease activity,” Tran says. Potentially the test could be used across many other disease states. I think thats the most exciting part, that its not just for one disease, but it could be a fit for multiple diseases.”

Having checked off a number of accomplishments on her academic mystical” to-do list, Tran was eager to explore new avenues where she could have a wider global impact, first at Gilead and now at Glympse, which offers her the opportunity to speak a different language” and start a new list.

Thats the beauty of it — you can make new lists, and your lists should change, and maybe you wont be the first author, but youll be on the author list,” she says. So you can change your list and you can modify your list; thats the beauty of a long career where youre willing to take some risks … and end up doing things that surprise you with how amazing they can be for your development.”

Im a life-long learner,” Tran says. I wanted to be able to do something very different. Going into industry and the life sciences was a career leap that I was willing to make at that point.”

Here, Tran shares her personal story that led to a career in medicine, how she learned to find her voice and how she has found personal and professional satisfaction working in the world of liver disease.

Welcome to WoW, the Woman of the Week podcast by PharmaVoice, powered by Industry Dive.

In this episode, Taren Grom, editor-in-chief emeritus at PharmaVoice meets with Dr. Tram Tran, chief medical officer at Glympse Bio.

Taren: Dr. Tran, welcome to the WoW podcast program.

Dr. Tran: Thanks very much for having me. I’m looking forward to a good conversation today.

Taren: Me too. How does being a physician scientist inform your role as chief medical officer at Glympse Bio?

Dr. Tran: I think that being a physician scientist, I think the important part of it for me is being a physician. I practiced for over 20 years and ran a liver transplant program at a hospital here in Los Angeles. I think the physician part of it is really important for informing my role because I think I bring the patient perspective because I took care of patients for so long. I think I bring the physician perspective because I think the clinician is closest to the patient to help us make decisions about things.

So I think being a chief medical officer really allows me to take that information and that background and really bring it to the science and work with our chief scientific officer to kind of meld the two things together — the incredible science that we can do in biotech, along with really what is the most important thing, which is the patient and the physician and how we can best deliver what we need to take care of patients.

Taren: Fantastic. Thank you for that. I understand that you are actually the first chief medical officer of the company. How are you defining this role?

Dr. Tran: I think I’m defining this role in the most pragmatic way possible, because I think sometimes when we are in a world of research or we’re doing a clinical trial or we’re doing studies, we just get very into the details and the weeds of that. So I really want to define the chief medical officer role as sort of bringing that pragmatism again, that patient perspective and not forgetting that’s our guiding light.

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